Drive north out of Spokane on Highway 395, then turn east (left) to reach portions of the river from downtown Spokane to the upper end of Long Lake. Drive east from town to Interstate 90 and take the roads to the north to reach the section of river between Spokane and the Idaho border.
Boat Ramps are located at Nine Mile Falls (downstream from Spokane) and Myrtle Point (upstream from town). Food, gas, lodging, and tackle are available throughout the area. Riverside State Park, about seven miles west of Spokane on the north side of the river, has a limited number of tent and RV sites, showers, and other facilities.
The Spokane River is a tributary of the Columbia River, approximately 111 miles long, in northern Idaho and eastern Washington in the United States. It drains a low mountainous area east of the Columbia, passing through the city of Spokane, Washington.
The Spokane River runs from North Idaho through the city of Spokane in the Inland Pacific Northwest. It is a diverse fishery with several options available to the freshwater river angler.
The Spokane River supports wild rainbow trout from the Idaho border to Nine Mile Falls Dam. There were some past stockings of brown trout that support a small wild population from the Idaho border to Nine Mile Falls.
The Spokane River changes several times over the course of it’s journey, changing from a water with stone riffles, to deep water pockets, to the famous Spokane Falls, where Spokane got its start as a city and is the main attractions for tourists when visiting downtown Spokane.
The Spokane River contains mostly Rainbow and Brown trout. The rainbows vary in size from 8-13 inches typically. The browns are less common but tend to be on the larger size from 10-15 inches.
Wading as a method for fishing the Spokane River is not always possible, however there are some good spots for wading on the East end of the river from the Spokane Valley to Coeur d’Alene. There are also good spots were wading is possible if you go West of downtown and into the Riverside State Park. In this area there are several riffles and small pockets deep water where the Spokane River can be fished.
Special regulations, including wild fish release rules and restrictions on the use of bait, have helped make the Spokane River a respectable trophy-trout fishery in recent years. The stretch of river east of Spokane, which offers some beautiful trout water, is where I would recommend going if you really want to sample what this pretty river has to offer. The problem may be getting to the water, since brush crowds the bank in many areas. There are man made trails through it in some places, but in other spots you avoid the brush by staying in the river and wading.
Take along a good selection of Muddler Minnows and other streamer patterns if you plan on fly fishing in search of big fish. If you prefer casting hardware for your trout, try a quarter ounce Bangtail or Rooster Tail spinner or a 3/8 oz. Krocodile spoon. And remember you must use a single, barbless hook, so replace those trebles!. A limited number of hatchery rainbows are planter here every year to provide some put and take harvest. The river is open year around to fishing, but some of the best action is in the early spring (March and April), and late fall in (October and November).
Here is a good article I found on a Spokane River fly fisherman: